陈柏竹
陈柏竹,中山大学“百人计划”引进人才,生物医学工程学院副教授,硕士生导师,深圳市海外高层次人才,深圳市生物医学工程学会生物医学材料专业委员会委员。目前研究方向为工程化生物活性材料的构建及其功能化开展研究,迄今以第一作者、通讯作者在《Nature Chemical Biology》、《Journal of Controlled Release》等生物化学、药学、材料等领域高水平杂志发表相关研究成果,担任《Nature Communications》、《ACS Applied Materials & Interfaces》等期刊审稿人。
1.基本信息:
姓名:陈柏竹 Chen Baizhu
职称:副教授/硕士生导师;
邮箱:chenbzh8@mail.sysu.edu.cn
地址:广东省深圳市光明区公常路66号,中山大学深圳校区医学园2-407A;
2.个人简历:
Ø工作经历:
2024.4-至今,中山大学,生物医学工程学院,副教授;
2020.11-2024.4,中山大学,生物医学工程学院,“百人计划”助理教授;
Ø教育经历:
2012.8-2017.11,香港中文大学,化学系,博士;导师:吴奇(中科院院士);
2008.9-2012.7, 南开大学,化学学院,材料化学系,学士。
3.研究方向:
1)针对恶性肿瘤,设计开发用于联合治疗的纳米药物/基因递送系统;
2)设计开发工程化生物活性材料用于药物递送、肿瘤治疗、生物制备、生物传感等领域。
4.科研项目:
1) 国家自然科学基金-青年科学基金项目,主持,2024-2027;
2) 广东省基础与应用基础研究区域联合基金-青年基金,主持,2022-2025;
3) 深圳市优秀科技创新人才培养项目-优青项目,主持,2024-2027;
4) 深圳市科技创新委员会, 基础研究(面上项目),2022-2025;
5.代表论文:
1)Baizhu Chen, Wei Kang; Jing Sun; Runtao Zhu; Yue Yu; Aiguo Xia; Mei Yu; Meng Wang; Jinyu Han; Yixuan Chen; Lijun Teng; Qiong Tian; Yin Yu; Guanglin Li; Lingchong You; Zhiyuan Liu; Zhuojun Dai*, Programmable living assembly of materials by bacterial adhesion, Nature Chemical Biology, 2022, 18 (3), 289–294.
2)Chen Wang, Qiliner Feng, Si Shi, Yuxuan Qin, Hongli Lu, Peng Zhang, Jie Liu*, Baizhu Chen*, The Rational Engineered Bacteria Based Biohybrid Living System for Tumor Therapy. Advanced Healthcare Materials 2024, 2401538, 1–21.
3)Junjie Tang, Yadong Liu, Yifan Xue, Zhaozhong Jiang, Baizhu Chen*, Jie Liu* Endoperoxide‐enhanced Self‐assembled ROS Producer as Intracellular Prodrugs for Tumor Chemotherapy and Chemodynamic Therapy. Exploration, 2024, No. January, 20230127.
4)Chen Wang, Qiliner Feng, Hongli Lu, Qiubei He, Peng Zhang, Junjie Tang, Zhuoyin Liu, Jie Liu, Baizhu Chen*, Metabolic Regulating Enhanced Immunological Activating Nanocomposites for Tumor Microenvironment Normalization and Immunotherapy. Materterials Today Nano, 2024, 27 (August), 100509.
5)Miao Feng, Shuting Xiao, Zhuoyin Liu, Meiting Li, Xiaoge Zhang, Xiaomei Chen, Yaqian Zhang, Baizhu Chen*, Jie Liu*, Multifunctional Platinum-Doped Porous FeS2 Nanoparticles for Photothermal-Enhanced Photodynamic Ferroptosis Combination Therapy. Materterials Today Nano 2023, 23, 100371.
6)Baizhu Chen, Xiaoge Zhang, Lili Cheng, Xiaomei Chen, Junjie Tang, Peng Zhang, Chen Wang, Jie Liu*; Surface Programmed Bacteria as Photo-Controlled NO Generator for Tumor Immunological and Gas Therapy. J. Control. Release 2023, 353 (November 2022), 889–902.
7)Miao Feng, Meiting Li, Rui Dai, Junjie Tang, Xiaoge Zhang, Baizhu Chen*, Jie Liu*, Multifunctional FeS2@SRF@BSA nanoplatform for chemo-combined photothermal enhanced photodynamic/chemodynamic combination therapy, Biomaterials Science, 2022, 10, 258–269.
8)Baizhu Chen*, Chi Wu, Cationic Cell Penetrating Peptide Modified SNARE Protein VAMP8 as Free Chains for Gene Delivery, Biomaterials Science, 2018, 6, 2647-2655.
9)Baizhu Chen*, Lei Yu, Zhibo Li, Chi Wu*, Design of Free Triblock Polylysine-b-Polyleucine-b-Polylysine Chains for Gene Delivery, Biomacromolecules. 2018, 19, 1347–1357.
10)Baizhu Chen*, C. V Synatschke, V. Jérôme, A.H.E. Müller, R. Freitag*, Chi Wu, Co-transfection of star-shaped PDMAEMAs enhance transfection efficiency of protamine/pDNA complexes in the presence of serum, European Polymer Journal 2018, 103, 362–369.
11)Baizhu Chen*, Lei Yu, Zhibo Li, Characterization of complexes made of polylysine-polyleucine-polylysine and pDNA, Journal of Material Chemistry B, 2017, 5, 3842–3851.