黄璐
姓名:黄璐
邮箱:huanglu39@mail.sysu.edu.cn
办公地址:广东省深圳市光明区中山大学深圳校区医学园2-503b
教育背景:
2010/09-2014/06:清华大学,学士
2014/08-2018/07:香港科技大学,博士
工作经历:
2024/04-至今:中山大学,副教授
2019/10-2024/04:中山大学,助理教授(“百人计划”)
2018/08-2019/09:香港大学,博士后
研究方向:
微流控芯片、高通量技术、单细胞检测与分析、智能微生理芯片系统等。
代表性论文(第一作者/通讯作者):
1.D. Yang, Z. Yu, M. Zheng, W. Yang, Z. Liu, J. Zhou*, L. Huang*, Artificial intelligence-accelerated high-throughput screening of antibiotic combinations on a microfluidic combinatorial droplet system. Lab Chip 2023, 23, 3961. (封面文章,中科院1区,IF: 7.517)
2.J. Dong, J. Zhou, H. Tang, B. Chen, L. Huang*, Laser-guided programmable construction of cell-laden hydrogel microstructures for in vitro drug evaluation. Biofabrication 2023, 15, 045011.(中科院1区,IF: 11.061)
3.Z. Liu, Z. Yu, J. Dong, D. Yang, J. Li, Z. He, J. Zhou, L. Huang*, A pathomimetic colorectal cancer-on-a-chip for in vitro reconstitution of the primary colorectal cancer tumor, Adv. Mater. Technol. 2023, 8, 2200758. (封面文章, JCR Q1,IF: 8.856)
4.J. He, J. Zhou, J. Dong, Z. Su, L. Huang*. Revealing the effects of microwell sizes on the crystal growth kinetics of active pharmaceutical ingredients by deep learning, Chem. Eng. J. 2022, 428, 131986. (中科院1区,IF: 16.744.)
5.W. Yang, T. Li, S. Liao, J. Zhou*, L. Huang*, Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment. Trends Analyt. Chem. 2024, 172, 117569. (中科院1区,IF: 13.1)
6.J. Zhou, J. Dong, H. Hou, L. Huang*, J. Li*, High-throughput microfluidic systems accelerated by artificial intelligence for biomedical applications. Lab Chip 2024, 24, 1307.(中科院1区,IF: 7.517)
7.Y. Chen, B. Chen, J. Dong, D. Yang, H. Tang, L. Wen, J. Li, L. Huang*, J. Zhou*. A tough and bioadhesive injectable hydrogel formed with maleimidyl alginate and pristine gelatin. Carbohydr. Polym. 2024, 334, 122011.(中科院1区,IF: 11.2.)
8.B. Chen, J. Dong, M. Ruelas, X. Ye, J. He, R. Yao, Y. Fu, Y. Liu, J. Hu, T. Wu, C. Zhou, Y. Li, L. Huang*, Y.S. Zhang*, and J. Zhou*, Artificial intelligence-assisted high-throughput screening of printing conditions of hydrogel architectures for accelerated diabetic wound healing, Adv. Funct. Mater. 2022, 2201843. (中科院1区,IF: 19.924)
9.P. Zhou, J. He, L. Huang*, Z. Yu, Z. Su, X. Shi, J. Zhou*. Microfluidic high-throughput platforms for discovery of novel materials, Nanomaterials 2020, 10, 2514.(JCR Q1,IF: 5.719)
10.L. Huang*, D. Yang, Z. Yu, J. He, Y. Chen, J. Zhou*. Deep learning-aided high-throughput screening of time-resolved protein crystallization on programmable microliter-droplet systems, Chem. Eng. J. 2022, 450, 138267. (中科院1区,IF: 16.744.)
11.L. Huang, Z. Liu, J. He, J. Li, Z. Wang, J. Zhou*, Y. Chen*, AI-aided addressable dual-nested microwell-array platforms for high-throughput profiling of single-cell migration and proliferation, Cell Rep. Phys. Sci. 2023, 4, 101276. (JCR Q1,IF: 7.832)
12.L. Huang, Y. Chen*, J. Zhou*, Interrogation of single-cell communications on microfluidic platforms, Cell Rep. Phys. Sci. 2022, 3, 101129. (JCR Q1,IF: 7.832)
13.L. Huang, J. Zhou, Y. Chen, W. Li, X. Han and L. Wang*. Engineering microcapsules for simultaneous delivery of combinational therapeutics, Adv. Mater. Technol. 2020, 18, 1113-1120. (JCR Q1,IF: 8.856)
14.L. Huang, Y. Chen, L.-T. Weng, M. Leung, X. Xing, Z. Fan, and H. Wu*, Fast single-cell patterning for study of drug-induced phenotypic alterations of HeLa cells using time-of-flight secondary ion mass spectrometry, Anal. Chem. 2016, 88, 12196-12203. (中科院1区,IF: 8.008)
15.L. Huang, Y. Chen, Y. Chen, and H. Wu*, Centrifugation-assisted single-cell trapping in a truncated cone-shaped microwell array chip for the real-time observation of cellular apoptosis, Anal. Chem. 2015, 87, 12169-12176. (中科院1区,IF: 8.008)
16.L. Huang, Y. Chen, W. Huang, and H. Wu*, Cell pairing and polyethylene glycol (PEG)-mediated fusion using two-step centrifugation-assisted single-cell trapping (CAScT), Lab Chip 2018, 18,1113-1120. (中科院1区,IF: 7.517)
17.L. Huang, SA. Michael, Y. Chen, and H. Wu*, Current advances in highly multiplexed antibody-based single-cell proteomic measurements, Chem. Asian J. 2017, 12, 1680-1691. (JCR Q1,IF: 4.839)
18.Y. Chen, L. Huang, X. Dai, Q. Tian, M. Yu, M. Agheb, H. N. Chan, E. Poon, Z. Guo, K. R. Boheler, and H. Wu*, Facile formation of microporous chitosan hydrogel scaffolds for tissue engineering, J. Mater. Chem. B 2017, 5, 9291-9299. (Co-first author, JCR Q1,IF: 7.571)
书籍章节:
1.Y. Chen, L. Huang, K. Ren, X. Shi, and H. Wu*, Applications of smart microfluidic systems in tissue engineering, Smart Materials for Tissue Engineering 2017, 596-614. (Co-first author, Book chapter)
2.D. Wang, H. N. Chan, Z. Liu, SA. Michael, L, Li, D. B. Baniani, M. J. A. Tan, L. Huang, J. Wang, and H. Wu*, Recent developments in microfluidic-based point-of-care testing (POCT) diagnoses, nanotechnology and microfluidics 2019, 239-280.
部分发明专利(已授权专利):
1.黄璐、杨德钰、周建华,一种非侵入式的细胞活性分析方法,专利号:ZL20211 1315941.0。
2.黄璐、董建沛、余子铭、陈寅、周建华,一种单细胞配对的双层微井阵列芯片及其制备方法和应用,专利号:ZL202211043034.X。
3.黄璐、刘章财、周建华,一种器官芯片及其应用,专利号:ZL202111339858.7。
4.黄璐、周建华,一种嵌套式微井阵列芯片及其制备方法,专利号:ZL202111404997.3 。
5.黄璐,一种可降解核壳式氧化海藻酸钙凝胶微球及其制备方法和应用,专利号:ZL202010461600.3。
科研项目(项目负责人,主持):
1.中国自然科学基金青年科学基金项目,2021-2023,主持。(30万)
2.广东省自然科学基金面上项目,2023-2025,主持。(10万)
3.深圳市医学研究专项资金项目,2024-2026,主持。(80万)
4.深圳市优秀科技创新人才博士启动项目,2022-2024,主持。(30万)
5.深圳市高等院校稳定支持计划基础科学研究面上项目,2021-2022,主持。(16万)
6.企业横向项目,2024-2025,主持。(10万)
7.中山大学百人计划启动基金项目,2020-2022,主持。(60万)
8.中央高校基本科研业务费青年教师培育项目,2020-2022,主持。(15万)
荣誉奖项:
1.深圳市海外高层次人才
2.第九届中山大学教师教学竞赛二等奖(工科组)
3.中山大学生物医学工程学院青年教师教学竞赛一等奖(1/1)
4.2022年度中山大学优秀班主任
5.HKUST School of Science Postgraduate Research Excellent Award(1/3 in Chemistry)
6.Scholarship of Academic Excellence
7.The DuPont Scholarship
8.The Yongxi Zheng Scholarship
课堂教学:
主讲《生物医学光学》(校观摩课)、《光学成像与检测技术》、《生物医学检测基础》等本科及研究生课程。
教学论文:
1.黄璐, 周建华*. 生物医学光学课程思政融入式理论教学探索[J]. 高教学刊, 2023, 9(30), 115.
2.黄璐, 瞿祥猛, 霍新明, 周建华*. 融通交叉学科基础知识,立足前沿开拓源头创新——生物医学工程学科生物医学检测基础课程教学改革探讨[J]. 高教学刊, 2023, 9(32), 133.
教学项目:
1.中山大学教学质量工程建设项目,课程思政示范课程,生物医学光学,2023,主持。
2.中山大学教学质量工程建设项目,高等教育教学改革课程,《生物医学检测基础》课程教学改革探讨,2023,参与。
学术/社会兼职:
担任深圳市科创委科技专家、Biosensors(JCR Q1)期刊客座编辑及Lab on a Chip等期刊审稿人。
招生:
课题组欢迎积极上进、独立性和执行力强、认真细心、虚心好学的本科生/研究生加入,背景包括但不限于生物医学工程、生物、化学、机械、电子、计算机等。