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张加宾

 

个人介绍

        张加宾,中山大学副教授,博士生导师。主要从事用于人体组织器官修复的工程化干细胞技术及其机制的研究,已在Advanced ScienceBioactive MaterialsBiomaterialsBiofabricationACS NanoAdvanced Functional Materials等本领域权威SCI期刊发表论文22篇,其中(共同)第一作者14篇,共同通讯作者1, 总影响因子282.5,总引用次数超1000次,H-index 18获中国发明专利授权2项。为Biofabrication2020/2021/2022/2024年杰出审稿人)、Biomedical Materials2022年杰出审稿人,Peer Review Advisory Panel member)、Journal of Materials Chemistry BJournal of Tissue EngineeringSCI期刊的独立审稿人,2023Wiley中国开放科学优秀作者。

 

个人信息(Personal Information

姓名(Name):张加宾(Zhang, Jiabin

职称(Title):副教授/博士生导师(Associate Professor

电子邮箱(E-mail): zhangjb67@mail.sysu.edu.cn

地址(Office):广东省深圳市光明区公常路66号,中山大学深圳校区医学园2-317

 

教育工作经历(Education & Working Experience

202601-至今

中山大学生物医学工程学院

副教授

202309-202511

澳大利亚蒙纳士大学

Research Fellow

202009-202308

中山大学附属第三医院

博士后

201508- 201912

澳大利亚阿德雷德大学

博士

201309- 201410

英国邓迪大学

硕士

200909- 201306

天津医科大学

学士

 

研究方向(Research Interests

1.类器官形成与演进的机制及其整合器官芯片用于药物筛选与疾病治疗的研究

2.基于各类3D打印技术(双光子聚合、近场直写等)的组织工程研究

3.智能型生物医用材料调控干细胞分化的机制及其治疗骨、肝等器官损伤的研究

 

科研项目(Research Funding

1.中山大学人才引进启动经费,2026.01–2028.12主持,在研)

2.广东省自然科学基金-面上项目,2023.01-2025.12主持,结题)

3.粤穗区域联合基金-青年基金项目,2022.10-2025.09主持,结题)

4.中国博士后科学基金-面上资助,2020.11-2023.9主持,结题)

5.中国博士后国(境)外交流项目-引进项目,2020.11-2022.10主持,结题)

6.国家自然科学基金-面上项目,2024.01-2027.12(参与,在研)

7.国家自然科学基金-面上项目,2023.01-2026.12(参与,在研)

 

论著(Publications

主要研究成果(*通讯作者;#同等贡献)

1.J. Zhang, X. Chen, Y. Chai, Y. Jin, F. Li, C. Zhuo, Y. Xu, H. Wang, E. Ju, Y. Lao, X. Xie*, M. Li*, Y. Tao*, Mesenchymal stromal/stem cell spheroid-derived extracellular vesicles advance the therapeutic efficacy of 3D-printed vascularized artificial liver lobules in liver failure treatment. Bioactive Materials 2025, 49: 121-139.

2.J. Zhang#, X. Chen#, Y. Chai, C. Zhuo, Y. Xu, T. Xue, D. Shao, Y. Tao*, M. Li*, 3D Printing of a Vascularized Mini-Liver Based on the Size-Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure. Advanced Science 2024, 11(17): 2309899. (封面文章)

3.J. Zhang, Y. Xu, C. Zhuo, R. Shi, H. Wang, Z. Hu, H. Chan, H. Kim, Y. Tao*, M. Li*, Highly efficient fabrication of functional hepatocyte spheroids by a magnetic system for the rescue of acute liver failure. Biomaterials 2023, 294: 122014.

4.Y. Jin#, J. Zhang#, Y. Xu, K. Yi, F. Li, H. Zhou, H. Wang, H. Chan, Y. Lao, S. Lv, Y. Tao*, M. Li*, Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure. Bioactive Materials 2023, 28: 112-131.

5.J. Zhang#, M. Zhang#, R. Lin, Y. Du, L. Wang, Q. Yao*, A. Zannettino*, H. Zhang*, Chondrogenic preconditioning of mesenchymal stem/stromal cells within a magnetic scaffold for osteochondral repair. Biofabrication 2022, 14: 025020.

6.F. Li#, J. Zhang#, K. Yi#, H. Wang, H. Wei, H. Chan, Y. Tao*, M. Li*, Delivery of stem cell secretome for therapeutic applications. ACS Applied Bio Materials 2022, 5: 2009-2030.

7.R. Su#, Y. Zhang#, J. Zhang#, H. Wang, Y. Luo, H. Chan, Y. Tao*, Z. Chen*, M. Li*, Nanomedicine to advance the treatment of bacteria-induced acute lung injury. Journal of Materials Chemistry B 2021 9(44): 9100-9115.

8.Y. Qin#, Y. Lao#, H. Wang#, J. Zhang*, K. Yi, Z. Chen, J. Han, W. Song*, Y. Tao*, M. Li*, Combatting Helicobacter pylori with oral nanomedicines. Journal of Materials Chemistry B 2021 9(48): 9826-9838.

9.J. Zhang, H. Chan, H. Wang, D. Shao, Y. Tao*, M. Li*, Stem cell therapy and tissue engineering strategies using cell aggregates and decellularized scaffolds for the rescue of liver failure. Journal of Tissue Engineering 2021, 12: 1-22.

10.J. Zhang, S. Yun, Y. Du, A. Zannettino*, H. Zhang*, Hydrogel-based preparation of cell aggregates for biomedical applications. Applied Materials Today 2020, 20: 100747.

11.J. Zhang, S. Yun, Y. Du, A. Zannettino*, H. Zhang*, Fabrication of a cartilage patch by fusing hydrogel-derived cell aggregates onto electrospun film. Tissue Engineering Part A 2020, 26: 0318.

12.J. Zhang, S. Yun, B. Jing, Y. Du*, A. Zannettino*, H. Zhang*, 3D printing of a thermosensitive hydrogel for skin tissue engineering: a proof of concept study. Bioprinting 2020, 19: e00089.

13.J. Zhang, M. Zhang, R. Lin, S. Yun, Y. Du, L. Wang, Q. Yao*, A. Zannettino*, H. Zhang*, Allogeneic primary mesenchymal stem/stromal cell aggregates within poly(N-isopropylacrylamide-co-acrylic acid) hydrogel for osteochondral regeneration. Applied Materials Today 2019, 18: 100487.

14.J. Zhang, S. Yun, J. Bi, S. Dai, Y. Du, A. Zannettino*, H. Zhang*, Enhanced multi-lineage differentiation of human mesenchymal stem/stromal cells within poly(N-isopropylacrylamide-acrylic acid) microgel-formed three-dimensional constructs. Journal of Materials Chemistry B 2018, 6(12): 1799-1814.

15.J. Zhang, H. Zhang*, X. Xu, CHAPTER 17 Smart materials to regulate the fate of stem cells. smart materials for tissue engineering: applications, The Royal Society of Chemistry 2017: 473-504.

 

荣誉奖项(Awards

1.2020/2021/2022/2024Biofabrication杂志杰出审稿人

2.2022Biomedical Materials杂志杰出审稿人

3.2023Wiley中国开放科学优秀作者

4.2019年澳大利亚阿德雷德大学优秀博士论文

5.2015-2019年澳大利亚阿德雷德大学四年制博士全额奖学金

6.2018年澳大利亚阿德雷德大学国际交流奖学金

7.2018年澳大利亚阿德雷德大学研究奖学金

8.2013/2014英国邓迪大学Erasmus学生交流实习项目奖学金

 

招聘与招生(Join Us

        课题组长期招聘具有材料、机械、生物医学相关背景的博士后;欢迎报考课题组硕士和博士研究生;欢迎本科生加入课题组开展科研训练和毕业设计。感兴趣者请将个人简历发送至邮箱zhangjb67@mail.sysu.edu.cn